/* sbd.css —— 合成生物学设计平台页面版式。颜色只走 var(--vx-*)（色值入口 vendor/vx/vx.css），半透明用 color-mix。 */
*{box-sizing:border-box}
html{scroll-behavior:smooth;scroll-padding-top:68px}
body{margin:0;background:var(--vx-paper);color:var(--vx-ink);font-family:var(--vx-font);font-size:15px;line-height:1.65;-webkit-font-smoothing:antialiased}
a{color:var(--vx-brand);text-decoration-thickness:1px;text-underline-offset:3px}
h1,h2,h3{margin:0;font-weight:600;line-height:1.25}
code,.mono{font-family:ui-monospace,"SF Mono",Menlo,monospace;font-size:.92em}
:focus-visible{outline:2px solid var(--vx-brand);outline-offset:2px;border-radius:4px}
[hidden]{display:none!important}
.num{font-variant-numeric:tabular-nums}

/* 顶栏 */
.topbar{position:sticky;top:0;z-index:30;display:flex;align-items:center;gap:20px;padding:0 28px;height:56px;background:color-mix(in srgb,var(--vx-paper) 88%,transparent);backdrop-filter:blur(10px);border-bottom:1px solid var(--vx-line)}
.brand{display:flex;align-items:center;gap:10px;font-weight:600;font-size:16px;color:var(--vx-ink);text-decoration:none}
.brand svg{width:28px;height:28px}
.topbar nav{display:flex;gap:4px;margin-left:12px}
.topbar nav a{padding:6px 12px;border-radius:8px;color:var(--vx-muted);text-decoration:none;font-size:14px}
.topbar nav a:hover{color:var(--vx-ink);background:var(--vx-brand-soft)}
.tb-right{margin-left:auto;display:flex;align-items:center;gap:8px}
.tbtn{display:inline-flex;align-items:center;gap:6px;padding:6px 12px;border:1px solid var(--vx-line);border-radius:8px;background:var(--vx-paper);color:var(--vx-ink);font:inherit;font-size:13px;cursor:pointer;text-decoration:none}
.tbtn:hover{background:var(--vx-brand-soft)}
.tbtn[aria-pressed="true"]{background:var(--vx-brand-soft);border-color:var(--vx-brand);color:var(--vx-brand)}

/* 按钮与表单 */
.btn{display:inline-flex;align-items:center;justify-content:center;gap:6px;padding:8px 16px;border:1px solid var(--vx-line);border-radius:8px;background:var(--vx-paper);color:var(--vx-ink);font:inherit;font-size:14px;cursor:pointer;text-decoration:none;transition:background .15s,border-color .15s}
.btn:hover{background:var(--vx-brand-soft);border-color:var(--vx-brand)}
.btn.primary{background:var(--vx-brand);border-color:var(--vx-brand);color:var(--vx-paper);font-weight:600}
.btn.primary:hover{filter:brightness(1.08)}
.btn.warn{border-color:var(--vx-warn);color:var(--vx-warn)}
.btn:disabled{opacity:.55;cursor:not-allowed}
.btn.sm{padding:4px 10px;font-size:13px}
label.f{display:block;margin:0 0 12px;font-size:13px;color:var(--vx-muted)}
label.f>span{display:block;margin-bottom:4px}
.in,select.in,textarea.in{width:100%;padding:8px 10px;border:1px solid var(--vx-line);border-radius:8px;background:var(--vx-paper);color:var(--vx-ink);font:inherit;font-size:14px}
textarea.in{min-height:96px;resize:vertical;font-family:ui-monospace,"SF Mono",Menlo,monospace;font-size:13px}
.in:focus{outline:2px solid var(--vx-brand);outline-offset:0;border-color:var(--vx-brand)}
.hint{font-size:12.5px;color:var(--vx-muted);margin-top:4px}
.row{display:flex;gap:12px;flex-wrap:wrap;align-items:center}
.grow{flex:1 1 auto}
.checks{display:flex;flex-wrap:wrap;gap:6px 14px}
.checks label{display:inline-flex;gap:6px;align-items:center;font-size:13.5px;color:var(--vx-ink)}
.two{display:grid;grid-template-columns:1fr 1fr;gap:10px}

/* 卡片、表格、标签 */
.card{background:var(--vx-paper);border:1px solid var(--vx-line);border-radius:12px;padding:18px 20px}
.card.panel{background:var(--vx-panel)}
.card>h3,.card>.h3{font-size:16px;margin-bottom:10px}
.card>.sub{margin:-4px 0 12px;font-size:13px;color:var(--vx-muted)}
.tblw{overflow:auto;max-width:100%}
.tbl{width:100%;border-collapse:collapse;font-size:14px}
.tbl th{text-align:left;font-weight:600;color:var(--vx-muted);font-size:12.5px;padding:8px 10px;border-bottom:1px solid var(--vx-line);white-space:nowrap}
.tbl td{padding:8px 10px;border-bottom:1px solid color-mix(in srgb,var(--vx-line) 55%,transparent);vertical-align:top}
.tbl tr:hover td{background:var(--vx-panel)}
.tbl td.r,.tbl th.r{text-align:right;font-variant-numeric:tabular-nums}
.tbl tr.click{cursor:pointer}
.chip{display:inline-flex;align-items:center;gap:4px;padding:1px 9px;border:1px solid var(--vx-line);border-radius:999px;font-size:12.5px;color:var(--vx-muted);background:var(--vx-paper);white-space:nowrap}
.chip.ok{color:var(--vx-ok);border-color:var(--vx-ok)}
.chip.warn{color:var(--vx-warn);border-color:var(--vx-warn)}
.chip.brand{color:var(--vx-brand);border-color:var(--vx-brand)}
.chip.demo{color:var(--vx-warn);border-color:var(--vx-warn);background:color-mix(in srgb,var(--vx-warn) 8%,var(--vx-paper))}
.note{padding:12px 16px;border:1px solid var(--vx-line);border-left:4px solid var(--vx-brand);border-radius:8px;background:var(--vx-panel);font-size:14px}
.note.warn{border-left-color:var(--vx-warn)}
.note.err{border-color:var(--vx-warn);border-left-color:var(--vx-warn);color:var(--vx-warn)}
.note.ok{border-left-color:var(--vx-ok)}
.note+.note{margin-top:10px}
.empty{padding:36px 24px;text-align:center;border:1px dashed var(--vx-line);border-radius:12px;color:var(--vx-muted)}
.empty b{display:block;color:var(--vx-ink);font-size:16px;margin-bottom:6px}
.kv{display:grid;grid-template-columns:max-content 1fr;gap:6px 18px;font-size:14px;margin:0}
.kv dt{color:var(--vx-muted)}.kv dd{margin:0;word-break:break-all}
.seqbox{font-family:ui-monospace,"SF Mono",Menlo,monospace;font-size:12.5px;line-height:1.7;word-break:break-all;max-height:200px;overflow:auto;padding:10px 12px;border:1px solid var(--vx-line);border-radius:8px;background:var(--vx-panel);letter-spacing:.02em}
.seqbox .c0{color:var(--vx-ink)}.seqbox .c1{color:var(--vx-brand)}
.spin{display:inline-block;width:14px;height:14px;border:2px solid var(--vx-line);border-top-color:var(--vx-brand);border-radius:50%;animation:spin .8s linear infinite;vertical-align:-2px;margin-right:6px}
@keyframes spin{to{transform:rotate(360deg)}}
html.vx-static .spin{animation:none;border-top-color:var(--vx-brand)}

/* ───── 首页 ───── */
.hero{position:relative;overflow:hidden;border-bottom:1px solid var(--vx-line);background:var(--vx-panel)}
.hero-in{position:relative;max-width:1320px;margin:0 auto;padding:56px 32px 48px;display:grid;grid-template-columns:minmax(0,1fr) minmax(0,.95fr);gap:40px;align-items:center}
.hero h1{font-size:42px;letter-spacing:-.01em}
.hero h1 em{font-style:normal;color:var(--vx-brand)}
.hero .lead{margin:16px 0 0;font-size:16.5px;color:var(--vx-muted);max-width:620px}
.hero .cta{margin-top:24px;display:flex;gap:12px;flex-wrap:wrap}
.hero-fig{position:relative;border:1px solid var(--vx-line);border-radius:16px;background:var(--vx-paper);padding:12px}
.hero-fig figcaption{font-size:12.5px;color:var(--vx-muted);padding:2px 6px}
.hero-stats{display:grid;grid-template-columns:repeat(4,max-content);gap:6px 28px;margin-top:26px}
.hero-stats b{display:block;font-size:26px;font-weight:600;line-height:1.2;font-variant-numeric:tabular-nums}
.hero-stats span{font-size:12.5px;color:var(--vx-muted)}
.demo-tag{position:absolute;top:12px;left:12px;z-index:2}
.contact{background:var(--vx-ink);color:var(--vx-paper)}
.contact-in{max-width:1320px;margin:0 auto;padding:14px 32px;font-size:14.5px;display:flex;gap:10px;flex-wrap:wrap;align-items:center}
.sec{max-width:1320px;margin:0 auto;padding:60px 32px 0}
.sec>h2{font-size:28px}
.sec>.sub{margin:8px 0 22px;max-width:820px;color:var(--vx-muted);font-size:15.5px}
.stepbar{display:flex;gap:0;margin:0 0 18px;border:1px solid var(--vx-line);border-radius:10px;overflow:hidden;width:max-content;max-width:100%}
.stepbar button{padding:9px 18px;border:0;border-right:1px solid var(--vx-line);background:var(--vx-paper);color:var(--vx-ink);font:inherit;font-size:14px;cursor:pointer;display:flex;gap:8px;align-items:center}
.stepbar button:last-child{border-right:0}
.stepbar button i{font-style:normal;display:inline-grid;place-items:center;width:20px;height:20px;border-radius:50%;background:var(--vx-brand-soft);color:var(--vx-brand);font-size:12px;font-weight:600}
.stepbar button[aria-selected="true"]{background:var(--vx-brand);color:var(--vx-paper);font-weight:600}
.stepbar button[aria-selected="true"] i{background:var(--vx-paper);color:var(--vx-brand)}
.stage{position:relative;border:1px solid var(--vx-line);border-radius:12px;background:var(--vx-panel);padding:16px;min-height:340px}
.stage>.cap{margin:0 0 12px;font-size:14.5px;color:var(--vx-muted);max-width:900px}
.split{display:grid;grid-template-columns:minmax(0,1.5fr) minmax(0,1fr);gap:20px;align-items:start}
.cols3{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:16px}
.status-tbl td:first-child{font-weight:600;white-space:nowrap}
.st{display:inline-block;padding:1px 10px;border-radius:999px;font-size:12.5px;font-weight:600;border:1px solid;white-space:nowrap}
.st.done{color:var(--vx-ok);border-color:var(--vx-ok)}.st.demo{color:var(--vx-brand);border-color:var(--vx-brand)}.st.plan{color:var(--vx-muted);border-color:var(--vx-line)}.st.no{color:var(--vx-warn);border-color:var(--vx-warn)}
.foot{margin:72px auto 0;border-top:1px solid var(--vx-line);padding:28px 32px 40px;max-width:1320px;font-size:13px;color:var(--vx-muted)}

/* ───── 工作台 ───── */
.wb{display:grid;grid-template-columns:232px minmax(0,1fr);min-height:calc(100vh - 56px)}
.side{border-right:1px solid var(--vx-line);background:var(--vx-panel);padding:18px 12px;position:sticky;top:56px;height:calc(100vh - 56px);overflow:auto;display:flex;flex-direction:column;gap:2px}
.side h4{margin:14px 12px 4px;font-size:12px;font-weight:600;color:var(--vx-muted);letter-spacing:.04em}
.side h4:first-child{margin-top:0}
.side a{display:block;padding:8px 12px;border-radius:8px;color:var(--vx-ink);text-decoration:none;font-size:14px}
.side a:hover{background:var(--vx-brand-soft)}
.side a[aria-current="page"]{background:var(--vx-brand);color:var(--vx-paper);font-weight:600}
.side .eng{margin-top:auto;padding:10px 12px;font-size:12.5px;color:var(--vx-muted);border-top:1px solid var(--vx-line)}
.main{padding:26px 36px 64px;min-width:0;max-width:1480px}
.main>h1{font-size:25px;margin-bottom:4px}
.main>.sub{margin:0 0 18px;color:var(--vx-muted);max-width:900px}
.dz{display:grid;grid-template-columns:330px minmax(0,1fr);gap:20px;align-items:start}
.dz>.ctl{position:sticky;top:72px}
.grid2{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,1fr);gap:18px;align-items:start}
.stack{display:grid;gap:18px}
.kpis{display:grid;grid-template-columns:repeat(5,minmax(0,1fr));gap:12px}
.kpi{padding:12px 14px;border:1px solid var(--vx-line);border-radius:10px;background:var(--vx-paper)}
.kpi b{display:block;font-size:24px;font-weight:600;line-height:1.2;font-variant-numeric:tabular-nums}
.kpi span{font-size:12.5px;color:var(--vx-muted)}
.kpi small{display:block;font-size:12.5px;color:var(--vx-muted);margin-top:2px;font-variant-numeric:tabular-nums}
.view-in{animation:viewIn .28s ease-out both}
@keyframes viewIn{from{opacity:0;transform:translateY(6px)}to{opacity:1;transform:none}}
html.vx-static .view-in{animation:none}
.tabs{display:inline-flex;border:1px solid var(--vx-line);border-radius:10px;overflow:hidden;margin-bottom:14px}
.tabs button{padding:7px 16px;border:0;border-right:1px solid var(--vx-line);background:var(--vx-paper);color:var(--vx-ink);font:inherit;font-size:14px;cursor:pointer}
.tabs button:last-child{border-right:0}
.tabs button[aria-selected="true"]{background:var(--vx-brand);color:var(--vx-paper);font-weight:600}
.legend{display:flex;gap:14px;flex-wrap:wrap;font-size:12.5px;color:var(--vx-muted);margin:6px 0 0}
.legend i{display:inline-block;width:18px;height:3px;border-radius:2px;vertical-align:middle;margin-right:6px}
.drop{border:1.5px dashed var(--vx-line);border-radius:12px;padding:22px;text-align:center;color:var(--vx-muted);cursor:pointer}
.drop.over,.drop:hover{border-color:var(--vx-brand);background:var(--vx-brand-soft)}

/* ───── 可视化 ───── */
.viz svg{display:block;width:100%;height:auto;overflow:visible}
.viz text{font-family:var(--vx-font)}
.viz .ax{font-size:11px;fill:var(--vx-muted)}
.viz .lbl{font-size:12px;fill:var(--vx-ink)}
.viz .lead{stroke:var(--vx-line);stroke-width:1;fill:none}
/* 环形质粒图：弧段按组装顺序依次描出 */
.plasmid{display:grid;grid-template-columns:minmax(0,1.25fr) minmax(220px,1fr);gap:18px;align-items:center}
.plasmid .arc{fill:none;stroke-width:24;cursor:pointer;transition:stroke-width .15s,opacity .15s}
.plasmid .arc:hover,.plasmid .arc:focus,.plasmid .arc.on{stroke-width:31;outline:none}
.plasmid .ring{fill:none;stroke:var(--vx-line);stroke-width:1}
html.vx-js .plasmid:not(.in) .arc{stroke-dasharray:1 1;stroke-dashoffset:1}
html.vx-js .plasmid.in .arc{stroke-dasharray:1 1;stroke-dashoffset:0;transition:stroke-dashoffset .7s cubic-bezier(.45,.05,.25,1) calc(var(--i,0)*.55s),stroke-width .15s}
html.vx-js .plasmid:not(.in) .lbl,html.vx-js .plasmid:not(.in) .lead{opacity:0}
html.vx-js .plasmid.in .lbl,html.vx-js .plasmid.in .lead{opacity:1;transition:opacity .5s ease calc(var(--i,0)*.55s + .5s)}
html.vx-static .plasmid .arc,html.vx-static .plasmid .lbl,html.vx-static .plasmid .lead{stroke-dashoffset:0!important;opacity:1!important;transition:none!important}
.pinfo{border:1px solid var(--vx-line);border-radius:10px;padding:12px 14px;background:var(--vx-paper);font-size:13.5px;min-height:150px}
.pinfo h4{margin:0 0 6px;font-size:15px}
.pinfo .sw{display:inline-block;width:12px;height:12px;border-radius:3px;margin-right:6px;vertical-align:-1px}
.pinfo .sq{font-family:ui-monospace,Menlo,monospace;font-size:12px;word-break:break-all;color:var(--vx-muted);max-height:72px;overflow:auto;margin-top:6px}
/* 热图、曲线、条 */
.heat3{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:14px}
.heat3 h4{margin:0 0 4px;font-size:13.5px}
.hc{stroke:var(--vx-paper);stroke-width:1}
html.vx-js .heat3:not(.in) .hc{opacity:0}
html.vx-js .heat3.in .hc{opacity:1;transition:opacity .4s ease calc(var(--r,0)*.05s + var(--p,0)*.5s)}
html.vx-static .heat3 .hc{opacity:1!important;transition:none!important}
.gcl path.ln{fill:none;stroke-width:2;stroke-linejoin:round}
html.vx-js .gcl:not(.in) path.ln{stroke-dasharray:1 1;stroke-dashoffset:1}
html.vx-js .gcl.in path.ln{stroke-dasharray:1 1;stroke-dashoffset:0;transition:stroke-dashoffset 1.8s cubic-bezier(.45,.05,.25,1) calc(var(--i,0)*.4s)}
html.vx-static .gcl path.ln{stroke-dashoffset:0!important;transition:none!important}
.mbar{display:grid;grid-template-columns:150px minmax(0,1fr) 150px;gap:4px 14px;align-items:center;padding:6px 0;border-bottom:1px solid color-mix(in srgb,var(--vx-line) 50%,transparent);font-size:13.5px}
.mbar .nm{color:var(--vx-ink)}.mbar .nm small{display:block;color:var(--vx-muted);font-size:12px}
.mbar .tr{display:grid;gap:3px}
.mbar .tr i{display:block;height:9px;border-radius:5px;transform-origin:left;transition:transform .9s cubic-bezier(.2,.7,.2,1) calc(var(--i,0)*.06s)}
html.vx-js .mbars:not(.in) .tr i{transform:scaleX(0)}
html.vx-static .mbars .tr i{transform:none!important;transition:none!important}
.mbar .vals{font-variant-numeric:tabular-nums;font-size:12.5px;color:var(--vx-muted);text-align:right}
.mbar .vals b{color:var(--vx-ink);font-weight:600}
.pathflow .box{fill:var(--vx-paper);stroke:var(--vx-line);stroke-width:1.5}
.pathflow .box.hit{stroke:var(--vx-ok);stroke-width:2}.pathflow .box.miss{stroke:var(--vx-warn);stroke-dasharray:5 4;stroke-width:1.5}
.pathflow .edge{fill:none;stroke:var(--vx-brand);stroke-width:2}
html.vx-js .pathflow:not(.in) .edge{stroke-dasharray:1 1;stroke-dashoffset:1}
html.vx-js .pathflow.in .edge{stroke-dasharray:1 1;stroke-dashoffset:0;transition:stroke-dashoffset .9s ease calc(var(--i,0)*.35s)}
html.vx-js .pathflow:not(.in) .nd{opacity:0}
html.vx-js .pathflow.in .nd{opacity:1;transition:opacity .5s ease calc(var(--i,0)*.35s)}
html.vx-static .pathflow .edge{stroke-dashoffset:0!important;transition:none!important}
html.vx-static .pathflow .nd{opacity:1!important;transition:none!important}
.cassette{display:flex;gap:0;margin:6px 0 2px;flex-wrap:nowrap;overflow:hidden;border-radius:8px}
.cassette>div{padding:10px 8px;font-size:12.5px;text-align:center;color:var(--vx-paper);white-space:nowrap;overflow:hidden;text-overflow:ellipsis;min-width:0}
html.vx-js .cassette:not(.in)>div{opacity:0;transform:translateX(-12px)}
html.vx-js .cassette.in>div{opacity:1;transform:none;transition:opacity .5s ease calc(var(--i,0)*.25s),transform .5s ease calc(var(--i,0)*.25s)}
html.vx-static .cassette>div{opacity:1!important;transform:none!important;transition:none!important}
.frag{display:grid;grid-template-columns:50px minmax(0,1fr);gap:10px;align-items:center;margin:6px 0}
.frag .nm{font-size:12.5px;color:var(--vx-muted)}
.fbar{position:relative;height:30px;border-radius:6px;background:var(--vx-line);overflow:hidden}
.fbar i{position:absolute;top:0;bottom:0;border-right:2px solid var(--vx-paper);display:flex;align-items:center;justify-content:center;font-style:normal;font-size:11.5px;color:var(--vx-paper);overflow:hidden;white-space:nowrap}
.pill{display:inline-block;padding:0 6px;border-radius:4px;font-family:ui-monospace,Menlo,monospace;font-size:12.5px;background:var(--vx-brand-soft);color:var(--vx-brand)}
.pill.bad{background:color-mix(in srgb,var(--vx-warn) 14%,var(--vx-paper));color:var(--vx-warn)}
@media (max-width:1100px){.hero-in,.split,.grid2,.dz,.plasmid{grid-template-columns:minmax(0,1fr)}.hero h1{font-size:32px}.cols3,.heat3{grid-template-columns:minmax(0,1fr)}.kpis{grid-template-columns:repeat(2,minmax(0,1fr))}.dz>.ctl{position:static}.hero-stats{grid-template-columns:repeat(2,max-content)}.mbar{grid-template-columns:110px minmax(0,1fr)}.mbar .vals{grid-column:1/-1;text-align:left}}
@media (max-width:820px){.wb{grid-template-columns:minmax(0,1fr)}.side{position:static;height:auto;flex-direction:row;flex-wrap:wrap;border-right:0;border-bottom:1px solid var(--vx-line)}.side .eng,.side h4{display:none}.main{padding:20px 16px 48px}.topbar{padding:0 14px}.topbar nav{display:none}.sec{padding:40px 16px 0}.hero-in{padding:32px 16px}.contact-in{padding:12px 16px}}
.hero-fig .plasmid{grid-template-columns:minmax(0,1fr)}
.hero-fig .pinfo{min-height:0}
.tbl.nw td,.tbl.nw th{white-space:nowrap}